Adaptation to Oxygen

Oxygen sensors and neuronal adaptation to ischemia

Hypoxia research is in the focus, as three of its pioneers receive the Lasker Prize 2016 for their discovery of hypoxia-inducible transcription factors (HIFs) and prolyl-4-hydroxlase domain proteins (PHDs) as cellular oxygen sensors [1]. HIFs are heterodimers consisting of a labile α and a stable β unit. In the presence of molecular oxygen the α subunit is hydroxylated by PHDs leading to immedi...

Adaptation of Bacillus subtilis to oxygen limitation.

Bacillus subtilis grows anaerobically by at least two different pathways, respiration using nitrate as an electron acceptor and fermentation in the absence of electron acceptors. Regulatory mechanisms have evolved allowing cells to shift to these metabolic capabilities in response to changes in oxygen availability. These include transcriptional activation of fnr upon oxygen limitation, a proces...

Oxygen Minimum Zone Benthos: Adaptation and Community Response to Hypoxia

Mid-water oxygen minima ( 0.5ml l 1 dissolved O2) intercept the continental margins along much of the eastern Pacific Ocean, off west Africa and in the Arabian Sea and Bay of Bengal, creating extensive stretches of sea floor exposed to permanent, severe oxygen depletion. These seafloor oxygen minimum zones (OMZs) typically occur at bathyal depths between 200m and 1000m, and are major sites of c...

Adaptation of Horsesickness Virus to Tissue Culture

Iranian Adaptation and Narrative Transformation with Special Attention to Amir Naderi’s Adaptation of Sadeq Chubak’s Tangsir

This paper, while focused primarily on the narrative transformation of Sadeq Chubak’s Tangsir from novel to film adaptation, offers a general survey of adaptation history in Iran and also investigates the nature of Iranian adaptation from both foreign and domestic sources. Drawing on Gerard Genette’s theories of Narratology, especially his notion of hypertextuality, transpragma...